Tramadol 225mg


Tramadol is a synthetic opioid analgesic (painkiller) that is frequently prescribed to manage moderate to severe levels of pain—such as that experienced after surgery or in chronic conditions like arthritis. It is commonly marketed under one of its brand names, Ultram.



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Buy Tramadol online.Tramadol exhibits

an effect profile similar to that of opioid agonists,

and tramadol abuse seems to be a problem for a number of countries.

The relationship between tramadol and sexual

function appears to be controversial.

Men with premature ejaculation (PE)

may benefit from taking tramadol off label;

however, these patients live “on a knife’s edge”

and are exquisitely sensitive to develop other sexual dysfunctions.


To review the literature regarding
the problem of tramadol abuse and
its relationship with sexual function.


We searched electronic databases

from 1977 to September 2015, including


Academic Search Complete,

Cochrane Systematic Reviews Database,

and GoogleScholar using the following key words:

tramadol, sexual functions, and sexual dysfunction. Tramadoh online/

Main Outcome Measure

To define the supposed benefits and the

potential risks of tramadol on different sexual

functions including ejaculation, orgasm,

erection, desire, and testosterone levels.


Although tramadol is thought to have low

abuse and dependence potentials worldwide,

its abuse has become a serious problem in many countries,

particularly in the Middle East, Africa, and West Asia.

The benefit of tramadol in PE was reported in 11 clinical trials,

evaluated by 6 systematic reviews, 3 of which

pooled data in a meta-analysis.

The evidence base on erectile dysfunction,

decreased libido, hypogonadism, anorgasmia,

and risky sexual behaviors in

patients abusing tramadol is inadequate.


Tramadol has a potential for drug abuse.

If taken too much, seek immediate medical attention.

Overdose symptoms may include drowsiness,

shallow breathing, slow heartbeat, extreme weakness,

cold or clammy skin, fainting or coma.

Do not take Tramadol with other drugs or alcohol

without consulting the doctor.

Alcohol interaction with tramadol may result to

seizure therefore caution is advised when this drug is used.

Talk to the doctor before stopping the use of this

medication to avoid withdrawal symptoms.


Tramadol may offer a useful intervention for treating PE.

As all primary studies had suffered from selection,

allocation, performance, or assessment bias, additional

rigorous well-designed controlled trials are

warranted to further investigate the potentia

l long-term risks of tramadol and to determine the safe

and the effective minimum daily dose.

Clinical research on drug abuse and

sexual dysfunction is an emerging field.

To date, small numbers of studies

have been performed and further studies are warranted.

Additional information

Product quantity

300, 500, 750, 1000, 2500, 5000, 10000


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