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Buy Tramadol online.Tramadol exhibits
an effect profile similar to that of opioid agonists,
and tramadol abuse seems to be a problem for a number of countries.
The relationship between tramadol and sexual
function appears to be controversial.
Men with premature ejaculation (PE)
may benefit from taking tramadol off label;
however, these patients live “on a knife’s edge”
and are exquisitely sensitive to develop other sexual dysfunctions.
We searched electronic databases
from 1977 to September 2015, including
PubMed MEDLINE, EMBASE, EBCSO
Academic Search Complete,
Cochrane Systematic Reviews Database,
and GoogleScholar using the following key words:
tramadol, sexual functions, and sexual dysfunction.
Main Outcome Measure
To define the supposed benefits and the
potential risks of tramadol on different sexual
functions including ejaculation, orgasm,
erection, desire, and testosterone levels.
Although tramadol is thought to have low
abuse and dependence potentials worldwide,
its abuse has become a serious problem in many countries,
particularly in the Middle East, Africa, and West Asia.
The benefit of tramadol in PE was reported in 11 clinical trials,
evaluated by 6 systematic reviews, 3 of which
pooled data in a meta-analysis.
The evidence base on erectile dysfunction,
decreased libido, hypogonadism, anorgasmia,
and risky sexual behaviors in
patients abusing tramadol is inadequate.
Tramadol has a potential for drug abuse.
If taken too much, seek immediate medical attention.
Overdose symptoms may include drowsiness,
shallow breathing, slow heartbeat, extreme weakness,
cold or clammy skin, fainting or coma.
Do not take Tramadol with other drugs or alcohol
without consulting the doctor.
Alcohol interaction with tramadol may result to
seizure therefore caution is advised when this drug is used.
Talk to the doctor before stopping the use of this
medication to avoid withdrawal symptoms.
Tramadol may offer a useful intervention for treating PE.
As all primary studies had suffered from selection,
allocation, performance, or assessment bias, additional
rigorous well-designed controlled trials are
warranted to further investigate the potentia
l long-term risks of tramadol and to determine the safe
and the effective minimum daily dose.
Clinical research on drug abuse and
sexual dysfunction is an emerging field.
To date, small numbers of studies
have been performed and further studies are warranted.